Dialogue with the Devil

Fisher's game with the devil.

The publication of Fisher's correspondence on statistics has shed new light on his views on randomization. Quotations from this correspondence and from other works of Fisher are used to illustrate the role of randomization in clinical trials. It is concluded that Fisher's views not only are coherent but, despite having been developed over 60 years ago and with particular reference to agricultur...

Multi-Party Quantum Dialogue with the Capability to Expand the Number of Users at Runtime

Quantum dialogue is a type of quantum communication in which users can simultaneously send messages to each other. The earliest instances of quantum dialogue protocols faced security problems such as information leakage and were vulnerable to intercept and resend attacks. Therefore, several protocols have been presented that try to solve these defects. Despite these improvements, the quantum di...

The Tasmanian Devil and Devil Facial Tumour Disease

The global extirpation of the world’s apex predator fauna is consistently highlighting their important functional role in preserving biodiversity and maintaining ecosystem resilience. Apex predator declines and extinctions are promoting more invasive and homogenised ecosystem states, linked with secondary species extinctions, changes to community composition, and redefined carnivore guilds. In ...

Telomerase: The Devil Inside

High telomerase activity is detected in nearly all human cancers but most human cells are devoid of telomerase activity. There is well-documented evidence that reactivation of telomerase occurs during cellular transformation. In humans, tumors can rely in reactivation of telomerase or originate in a telomerase positive stem/progenitor cell, or rely in alternative lengthening of telomeres, a tel...

Poisoning the Devil